Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Demyelinating Diseases'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Demyelinating Diseases
        • Hereditary Central Nervous System Demyelinating Diseases
          • Fucosidosis (GDGDB) [FUCA1]
          • Hurler-Scheie syndrome (GDGDB) [IDUA]
          • Mucopolysaccharidosis II (GDGDB) [IDS]
          • Sanfilippo syndrome A (GDGDB) [SGSH]
          • Sanfilippo syndrome B (GDGDB) [NAGLU]
          • Sanfilippo syndrome C (GDGDB) [HGSNAT]
          • Sanfilippo syndrome D (GDGDB) [GNS]
          • Morquio syndrome A (GDGDB) [GALNS]
          • Morquio syndrome B (GDGDB) [GLB1]
          • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
          • GM1-gangliosidosis, type I (GDGDB) [GLB1]
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
          • GM1-gangliosidosis, type III (GDGDB) [GLB1]
          • Tay-Sachs disease (GDGDB) [HEXA]
            • Tay-Sachs disease, infantile form [HEXA]
          • Sandhoff disease (GDGDB) [HEXB]
            • Sandhoff disease, infantile form [HEXB]
          • Krabbe disease (GDGDB) [GALC]
          • Metachromatic leukodystrophy (GDGDB) [ARSA]
          • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
          • Combined saposin deficiency (GDGDB) [PSAP]