Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'GM1-gangliosidosis, type II'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation
  • Disorders of sphingolipid metabolism and other lipid storage disorders
    • Sphingolipidosis
      • Gangliosidosis
        • GM1 gangliosidosis
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Cardiovascular Diseases
      • Heart Diseases
        • Cardiomegaly
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • GM1-gangliosidosis, type II (GDGDB) [GLB1]
    • Digestive System Diseases
      • Liver Diseases
        • Hepatomegaly
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
    • Eye Diseases
      • Corneal Diseases
        • Corneal Opacity
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
      • Retinal Diseases
        • Retinal Degeneration
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
    • Hemic and Lymphatic Diseases
      • Lymphatic Diseases
        • Splenic Diseases
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
    • Musculoskeletal Diseases
      • Bone Diseases
        • Bone Diseases, Developmental
          • Dysostoses
            • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • Spinal Diseases
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
      • Musculoskeletal Abnormalities
        • Craniofacial Abnormalities
          • Maxillofacial Abnormalities
            • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • GM1-gangliosidosis, type II (GDGDB) [GLB1]
      • Muscular Diseases
        • Muscle Weakness
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
    • Nervous System Diseases
      • Central Nervous System Diseases
        • Brain Diseases
          • Brain Diseases, Metabolic
            • Brain Diseases, Metabolic, Inborn
              • GM1-gangliosidosis, type II (GDGDB) [GLB1]
      • Demyelinating Diseases
        • Hereditary Central Nervous System Demyelinating Diseases
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
      • Neurologic Manifestations
        • Dyskinesias
          • Dystonia
            • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • Neurobehavioral Manifestations
          • Intellectual Disability
            • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • Neuromuscular Manifestations
          • Muscle Weakness
            • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • Seizures
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • Sensation Disorders
          • Vision Disorders
            • Blindness
              • GM1-gangliosidosis, type II (GDGDB) [GLB1]
    • Stomatognathic Diseases
      • Mouth Diseases
        • Periodontal Diseases
          • Gingival Diseases
            • Gingival Overgrowth
              • Gingival Hyperplasia
                • GM1-gangliosidosis, type II (GDGDB) [GLB1]
      • Stomatognathic System Abnormalities
        • Maxillofacial Abnormalities
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
  • Psychiatry and Psychology
    • Mental Disorders
      • Mental Disorders Diagnosed in Childhood
        • Developmental Disabilities
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
        • Intellectual Disability
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]