Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Intellectual Disability'  (Integration tree)

Pathogenesis (traditional nomenclature)

• Genetic disorders of glycan synthesis (traditional nomenclature)

Pathogenesis (new nomenclature)

• Genetic disorders of glycan synthesis (new nomenclature)

Genetic disorders of glycan synthesis (by systems, signs and symptoms)

• Genetic disorders of glycan synthesis (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Neurologic Manifestations
        • Neurobehavioral Manifestations
          • Intellectual Disability
            • PMM2-CDG (GDGDB) [PMM2]
              • PMM2-CDG, infantile multisystem stage [PMM2]
              • PMM2-CDG, late-infantile and childhood ataxia-intellectual disability stage [PMM2]
              • PMM2-CDG, adult stable disability stage [PMM2]
            • ALG6-CDG (GDGDB) [ALG6]
            • ALG3-CDG (GDGDB) [ALG3]
            • ALG12-CDG (GDGDB) [ALG12]
            • ALG2-CDG (GDGDB) [ALG2]
            • DPAGT1-CDG (GDGDB) [DPAGT1]
            • SLC35C1-CDG (GDGDB) [SLC35C1]
            • COG1-CDG [COG1]
            • COG8-CDG [COG8]
            • COG5-CDG [COG5]
            • TUSC3-CDG [TUSC3]
            • ATP6VOA2-CDG [ATP6V0A2]
            • POMT1/POMT2-CDG (cong. muscular dystrophy spectrum) (GDGDB) [POMT1,POMT2]
            • POMGNT1-CDG (cong. muscular dystrophy spectrum) (GDGDB) [POMGNT1]
            • Fukuyama congenital muscular dystrophy (GDGDB) [FKTN]
            • Muscular dystrophy, congenital, type 1C (GDGDB) [FKRP]
            • LARGE-CDG (cong. muscular dystrophy spectrum) [LARGE]
            • B4GALT7-CDG [B4GALT7]
            • B3GALTL-CDG [B3GALTL]
            • ST3GAL5-CDG [SIAT9]
            • ALG11-CDG [ALG11]
            • SRD5A3-CDG [SRD5A3]
            • Mental retardation, autosomal recessive 15 [MAN1B1]
            • Mental retardation, autosomal recessive 12 [ST3GAL3]
            • Temtamy preaxial brachydactyly syndrome [CHSY1]
            • Hyperphosphatasia with mental retardation syndrome 1 [PIGV]
  • Psychiatry and Psychology
    • Mental Disorders
      • Mental Disorders Diagnosed in Childhood
        • Intellectual Disability
          • PMM2-CDG (GDGDB) [PMM2]
            • PMM2-CDG, infantile multisystem stage [PMM2]
            • PMM2-CDG, late-infantile and childhood ataxia-intellectual disability stage [PMM2]
            • PMM2-CDG, adult stable disability stage [PMM2]
          • ALG6-CDG (GDGDB) [ALG6]
          • ALG3-CDG (GDGDB) [ALG3]
          • ALG12-CDG (GDGDB) [ALG12]
          • ALG2-CDG (GDGDB) [ALG2]
          • DPAGT1-CDG (GDGDB) [DPAGT1]
          • SLC35C1-CDG (GDGDB) [SLC35C1]
          • COG1-CDG [COG1]
          • COG8-CDG [COG8]
          • COG5-CDG [COG5]
          • TUSC3-CDG [TUSC3]
          • ATP6VOA2-CDG [ATP6V0A2]
          • POMT1/POMT2-CDG (cong. muscular dystrophy spectrum) (GDGDB) [POMT1,POMT2]
          • POMGNT1-CDG (cong. muscular dystrophy spectrum) (GDGDB) [POMGNT1]
          • Fukuyama congenital muscular dystrophy (GDGDB) [FKTN]
          • Muscular dystrophy, congenital, type 1C (GDGDB) [FKRP]
          • LARGE-CDG (cong. muscular dystrophy spectrum) [LARGE]
          • B4GALT7-CDG [B4GALT7]
          • B3GALTL-CDG [B3GALTL]
          • ST3GAL5-CDG [SIAT9]
          • ALG11-CDG [ALG11]
          • SRD5A3-CDG [SRD5A3]
          • Mental retardation, autosomal recessive 15 [MAN1B1]
          • Mental retardation, autosomal recessive 12 [ST3GAL3]
          • Temtamy preaxial brachydactyly syndrome [CHSY1]
          • Hyperphosphatasia with mental retardation syndrome 1 [PIGV]