Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Seizures'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Neurologic Manifestations
        • Seizures
          • Aspartylglucosaminuria (GDGDB) [AGA]
          • Fucosidosis (GDGDB) [FUCA1]
          • Beta-mannosidosis (GDGDB) [MANBA]
          • Sialidosis (GDGDB) [NEU1]
          • Schindler disease, type I (GDGDB) [NAGA]
          • Galactosialidosis (GDGDB) [CTSA]
          • Sanfilippo syndrome A (GDGDB) [SGSH]
          • Sanfilippo syndrome B (GDGDB) [NAGLU]
          • Sanfilippo syndrome C (GDGDB) [HGSNAT]
          • Sanfilippo syndrome D (GDGDB) [GNS]
          • GM1-gangliosidosis, type I (GDGDB) [GLB1]
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
          • GM1-gangliosidosis, type III (GDGDB) [GLB1]
          • Tay-Sachs disease (GDGDB) [HEXA]
          • Sandhoff disease (GDGDB) [HEXB]
          • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
          • Gaucher disease, type II (GDGDB) [GBA]
          • Gaucher disease, type III (GDGDB) [GBA]
          • Krabbe disease (GDGDB) [GALC]
            • Krabbe disease, infantile form [GALC]
            • Krabbe disease, late-onset form [GALC]
          • Metachromatic leukodystrophy (GDGDB) [ARSA]
          • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
          • Niemann-Pick disease, type A (GDGDB) [SMPD1]
          • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
          • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
          • Farber Lipogranulomatosis (GDGDB) [ASAH1]
            • Farber Lipogranulomatosis, type 5 [ASAH1]
          • Combined saposin deficiency (GDGDB) [PSAP]