Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Sensation Disorders'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Neurologic Manifestations
        • Sensation Disorders
          • Hearing Disorders
            • Hearing Loss
              • Alpha-mannosidosis (GDGDB) [MAN2B1]
              • Beta-mannosidosis (GDGDB) [MANBA]
              • Sialidosis (GDGDB) [NEU1]
              • Schindler disease, type II (GDGDB) [NAGA]
              • Galactosialidosis (GDGDB) [CTSA]
              • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Hurler syndrome (GDGDB) [IDUA]
              • Hurler-Scheie syndrome (GDGDB) [IDUA]
              • Scheie syndrome (GDGDB) [IDUA]
              • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Sanfilippo syndrome A (GDGDB) [SGSH]
              • Sanfilippo syndrome B (GDGDB) [NAGLU]
              • Sanfilippo syndrome C (GDGDB) [HGSNAT]
              • Sanfilippo syndrome D (GDGDB) [GNS]
              • Morquio syndrome A (GDGDB) [GALNS]
              • Morquio syndrome B (GDGDB) [GLB1]
              • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
              • Mucopolysaccharidosis VII (GDGDB) [GUSB]
              • Tay-Sachs disease (GDGDB) [HEXA]
              • Sandhoff disease (GDGDB) [HEXB]
              • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
              • Fabry disease (GDGDB) [GLA]
              • Krabbe disease (GDGDB) [GALC]
                • Krabbe disease, infantile form [GALC]
                • Krabbe disease, late-onset form [GALC]
              • Multiple sulfatase deficiency (GDGDB) [SUMF1]
              • Metachromatic leukodystrophy (GDGDB) [ARSA]
              • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
            • Tinnitus
              • Fabry disease (GDGDB) [GLA]
          • Somatosensory Disorders
            • Hypesthesia
              • Beta-mannosidosis (GDGDB) [MANBA]
              • Schindler disease, type II (GDGDB) [NAGA]
              • Metachromatic leukodystrophy (GDGDB) [ARSA]
              • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
            • Paresthesia
              • Fabry disease (GDGDB) [GLA]
          • Vision Disorders
            • Blindness
              • Schindler disease, type I (GDGDB) [NAGA]
              • Galactosialidosis (GDGDB) [CTSA]
              • Hurler syndrome (GDGDB) [IDUA]
              • Hurler-Scheie syndrome (GDGDB) [IDUA]
              • Scheie syndrome (GDGDB) [IDUA]
              • Morquio syndrome A (GDGDB) [GALNS]
              • Morquio syndrome B (GDGDB) [GLB1]
              • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
              • Mucopolysaccharidosis VII (GDGDB) [GUSB]
              • GM1-gangliosidosis, type I (GDGDB) [GLB1]
              • GM1-gangliosidosis, type II (GDGDB) [GLB1]
              • GM1-gangliosidosis, type III (GDGDB) [GLB1]
              • Tay-Sachs disease (GDGDB) [HEXA]
              • Sandhoff disease (GDGDB) [HEXB]
              • GM2-gangliosidosis, AB variant (GDGDB) [GM2A]
              • Krabbe disease (GDGDB) [GALC]
              • Metachromatic leukodystrophy (GDGDB) [ARSA]
              • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
            • Vision, Low
              • Sialidosis (GDGDB) [NEU1]
              • Mucopolysaccharidosis II (GDGDB) [IDS]
              • Sanfilippo syndrome A (GDGDB) [SGSH]
              • Sanfilippo syndrome B (GDGDB) [NAGLU]
              • Sanfilippo syndrome C (GDGDB) [HGSNAT]
              • Sanfilippo syndrome D (GDGDB) [GNS]
              • Gaucher disease, type IIIC (GDGDB) [GBA]