Legend:

• Concept Types
  • target (single disease)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Sialidosis'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation
  • Disorders of glycoprotein metabolism
    • Defects in glycoprotein degradation
      • Sialidosis (GDGDB) [NEU1]
        • Sialidosis type I [NEU1]
        • Sialidosis type II [NEU1]
          • Sialidosis type II, congenital form [NEU1]
          • Sialidosis type II, infantile form [NEU1]
          • Sialidosis type II, juvenile form [NEU1]

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Digestive System Diseases
      • Liver Diseases
        • Hepatomegaly
          • Sialidosis (GDGDB) [NEU1]
    • Eye Diseases
      • Retinal Diseases
        • Retinal Degeneration
          • Sialidosis (GDGDB) [NEU1]
            • Sialidosis type I [NEU1]
            • Sialidosis type II [NEU1]
              • Sialidosis type II, infantile form [NEU1]
              • Sialidosis type II, juvenile form [NEU1]
    • Hemic and Lymphatic Diseases
      • Lymphatic Diseases
        • Splenic Diseases
          • Sialidosis (GDGDB) [NEU1]
    • Musculoskeletal Diseases
      • Bone Diseases
        • Bone Diseases, Developmental
          • Dwarfism
            • Sialidosis (GDGDB) [NEU1]
          • Dysostoses
            • Sialidosis (GDGDB) [NEU1]
        • Bone Diseases, Metabolic
          • Mucolipidoses
            • Sialidosis (GDGDB) [NEU1]
      • Musculoskeletal Abnormalities
        • Craniofacial Abnormalities
          • Maxillofacial Abnormalities
            • Sialidosis (GDGDB) [NEU1]
    • Neoplasms
      • Neoplasms by Histologic Type
        • Neoplasms, Vascular Tissue
          • Angiokeratoma
            • Sialidosis (GDGDB) [NEU1]
    • Nervous System Diseases
      • Central Nervous System Diseases
        • Brain Diseases
          • Brain Diseases, Metabolic
            • Brain Diseases, Metabolic, Inborn
              • Sialidosis (GDGDB) [NEU1]
        • Movement Disorders
          • Dyskinesias
            • Sialidosis (GDGDB) [NEU1]
      • Neurologic Manifestations
        • Dyskinesias
          • Ataxia
            • Sialidosis (GDGDB) [NEU1]
          • Myoclonus
            • Sialidosis (GDGDB) [NEU1]
          • Tremor
            • Sialidosis (GDGDB) [NEU1]
        • Gait Disorders, Neurologic
          • Sialidosis (GDGDB) [NEU1]
        • Neurobehavioral Manifestations
          • Intellectual Disability
            • Sialidosis (GDGDB) [NEU1]
              • Sialidosis type II [NEU1]
        • Seizures
          • Sialidosis (GDGDB) [NEU1]
        • Sensation Disorders
          • Hearing Disorders
            • Hearing Loss
              • Sialidosis (GDGDB) [NEU1]
          • Vision Disorders
            • Vision, Low
              • Sialidosis (GDGDB) [NEU1]
    • Otorhinolaryngologic Diseases
      • Ear Diseases
        • Hearing Disorders
          • Hearing Loss
            • Sialidosis (GDGDB) [NEU1]
    • Pathological Conditions, Signs and Symptoms
      • Signs and Symptoms
        • Edema
          • Hydrops Fetalis
            • Sialidosis (GDGDB) [NEU1]
        • Mobility Limitation
          • Sialidosis (GDGDB) [NEU1]
    • Stomatognathic Diseases
      • Mouth Diseases
        • Periodontal Diseases
          • Gingival Diseases
            • Gingival Overgrowth
              • Gingival Hyperplasia
                • Sialidosis (GDGDB) [NEU1]
      • Stomatognathic System Abnormalities
        • Maxillofacial Abnormalities
          • Sialidosis (GDGDB) [NEU1]
  • Psychiatry and Psychology
    • Mental Disorders
      • Mental Disorders Diagnosed in Childhood
        • Intellectual Disability
          • Sialidosis (GDGDB) [NEU1]
            • Sialidosis type II [NEU1]