Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Bone Diseases'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Musculoskeletal Diseases
      • Bone Diseases
        • Bone Diseases, Developmental
          • Dwarfism
            • Sialidosis (GDGDB) [NEU1]
            • Galactosialidosis (GDGDB) [CTSA]
            • Mucolipidosis III (alpha/beta) (GDGDB) [GNPTAB]
            • Hurler syndrome (GDGDB) [IDUA]
            • Hurler-Scheie syndrome (GDGDB) [IDUA]
            • Scheie syndrome (GDGDB) [IDUA]
            • Mucopolysaccharidosis II (GDGDB) [IDS]
            • Sanfilippo syndrome A (GDGDB) [SGSH]
            • Sanfilippo syndrome B (GDGDB) [NAGLU]
            • Sanfilippo syndrome C (GDGDB) [HGSNAT]
            • Sanfilippo syndrome D (GDGDB) [GNS]
            • Morquio syndrome A (GDGDB) [GALNS]
            • Morquio syndrome B (GDGDB) [GLB1]
            • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
            • Mucopolysaccharidosis VII (GDGDB) [GUSB]
            • Niemann-Pick disease, type B (GDGDB) [SMPD1]
          • Dysostoses
            • Aspartylglucosaminuria (GDGDB) [AGA]
            • Fucosidosis (GDGDB) [FUCA1]
            • Alpha-mannosidosis (GDGDB) [MAN2B1]
            • Beta-mannosidosis (GDGDB) [MANBA]
            • Sialidosis (GDGDB) [NEU1]
            • Schindler disease
            • Galactosialidosis (GDGDB) [CTSA]
            • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
            • Mucolipidosis III (alpha/beta) (GDGDB) [GNPTAB]
            • Hurler syndrome (GDGDB) [IDUA]
            • Hurler-Scheie syndrome (GDGDB) [IDUA]
            • Scheie syndrome (GDGDB) [IDUA]
            • Mucopolysaccharidosis II (GDGDB) [IDS]
            • Sanfilippo syndrome A (GDGDB) [SGSH]
            • Sanfilippo syndrome B (GDGDB) [NAGLU]
            • Sanfilippo syndrome C (GDGDB) [HGSNAT]
            • Sanfilippo syndrome D (GDGDB) [GNS]
            • Morquio syndrome A (GDGDB) [GALNS]
            • Morquio syndrome B (GDGDB) [GLB1]
            • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
            • Mucopolysaccharidosis VII (GDGDB) [GUSB]
            • GM1-gangliosidosis, type I (GDGDB) [GLB1]
            • GM1-gangliosidosis, type II (GDGDB) [GLB1]
            • GM1-gangliosidosis, type III (GDGDB) [GLB1]
            • Sandhoff disease (GDGDB) [HEXB]
        • Bone Diseases, Metabolic
          • Mucolipidoses
            • Sialidosis (GDGDB) [NEU1]
            • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
            • Mucolipidosis III (alpha/beta) (GDGDB) [GNPTAB]
          • Osteoporosis
            • Aspartylglucosaminuria (GDGDB) [AGA]
            • Alpha-mannosidosis (GDGDB) [MAN2B1]
            • Mucolipidosis III (alpha/beta) (GDGDB) [GNPTAB]
            • Gaucher disease, type I (GDGDB) [GBA]
            • Gaucher disease, type III (GDGDB) [GBA]
            • Gaucher disease, type IIIC (GDGDB) [GBA]
        • Spinal Diseases
          • Spinal Curvatures
            • Kyphosis
              • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
              • Multiple sulfatase deficiency (GDGDB) [SUMF1]
          • Spinal Stenosis
            • Hurler syndrome (GDGDB) [IDUA]
            • Hurler-Scheie syndrome (GDGDB) [IDUA]
            • Scheie syndrome (GDGDB) [IDUA]
            • Mucopolysaccharidosis II (GDGDB) [IDS]
            • Morquio syndrome A (GDGDB) [GALNS]
            • Morquio syndrome B (GDGDB) [GLB1]
            • Mucopolysaccharidosis VI (GDGDB) (GDGDB) [ARSB]
            • Mucopolysaccharidosis VII (GDGDB) [GUSB]
          • Aspartylglucosaminuria (GDGDB) [AGA]
          • Alpha-mannosidosis (GDGDB) [MAN2B1]
          • Galactosialidosis (GDGDB) [CTSA]
          • GM1-gangliosidosis, type I (GDGDB) [GLB1]
          • GM1-gangliosidosis, type II (GDGDB) [GLB1]
          • GM1-gangliosidosis, type III (GDGDB) [GLB1]