Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Dyskinesias'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Central Nervous System Diseases
        • Movement Disorders
          • Dyskinesias
            • Aspartylglucosaminuria (GDGDB) [AGA]
            • Fucosidosis (GDGDB) [FUCA1]
            • Sialidosis (GDGDB) [NEU1]
            • Sanfilippo syndrome A (GDGDB) [SGSH]
            • Sanfilippo syndrome B (GDGDB) [NAGLU]
            • Sanfilippo syndrome C (GDGDB) [HGSNAT]
            • Sanfilippo syndrome D (GDGDB) [GNS]
            • Tay-Sachs disease (GDGDB) [HEXA]
            • Sandhoff disease (GDGDB) [HEXB]
            • Gaucher disease, type II (GDGDB) [GBA]
            • Krabbe disease (GDGDB) [GALC]
            • Metachromatic leukodystrophy (GDGDB) [ARSA]
            • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
            • Niemann-Pick disease, type A (GDGDB) [SMPD1]
            • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
            • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
            • Combined saposin deficiency (GDGDB) [PSAP]
      • Neurologic Manifestations
        • Dyskinesias
          • Ataxia
            • Aspartylglucosaminuria (GDGDB) [AGA]
            • Alpha-mannosidosis (GDGDB) [MAN2B1]
            • Sialidosis (GDGDB) [NEU1]
            • Galactosialidosis (GDGDB) [CTSA]
            • Tay-Sachs disease (GDGDB) [HEXA]
            • Sandhoff disease (GDGDB) [HEXB]
            • Metachromatic leukodystrophy (GDGDB) [ARSA]
            • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
            • Niemann-Pick disease, type A (GDGDB) [SMPD1]
            • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
            • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
          • Dystonia
            • GM1-gangliosidosis, type I (GDGDB) [GLB1]
            • GM1-gangliosidosis, type II (GDGDB) [GLB1]
            • GM1-gangliosidosis, type III (GDGDB) [GLB1]
            • Niemann-Pick disease, type A (GDGDB) [SMPD1]
            • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
            • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
          • Myoclonus
            • Sialidosis (GDGDB) [NEU1]
            • Galactosialidosis (GDGDB) [CTSA]
            • Farber Lipogranulomatosis (GDGDB) [ASAH1]
              • Farber Lipogranulomatosis, type 5 [ASAH1]
            • Combined saposin deficiency (GDGDB) [PSAP]
          • Tremor
            • Sialidosis (GDGDB) [NEU1]
            • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
            • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
          • Hyperkinesis
            • Combined saposin deficiency (GDGDB) [PSAP]