Legend:

• Concept Types
  • target (clinical findings)
  • classification term
  • pathway-based classification term
  • clinical findings
  • multiple types disease
  • single disease
  • disease type

'Speech Disorders'  (Integration tree)

Pathogenesis

• Genetic disorders of glycan degradation

Disorders by systems

• Genetic disorders of glycan degradation (by systems, signs and symptoms)
  • Diseases
    • Nervous System Diseases
      • Neurologic Manifestations
        • Neurobehavioral Manifestations
          • Communication Disorders
            • Language Disorders
              • Speech Disorders
                • Aspartylglucosaminuria (GDGDB) [AGA]
                • Alpha-mannosidosis (GDGDB) [MAN2B1]
                • Beta-mannosidosis (GDGDB) [MANBA]
                • Mucolipidosis II (alpha/beta) (GDGDB) [GNPTAB]
                • Sanfilippo syndrome A (GDGDB) [SGSH]
                • Sanfilippo syndrome B (GDGDB) [NAGLU]
                • Sanfilippo syndrome C (GDGDB) [HGSNAT]
                • Sanfilippo syndrome D (GDGDB) [GNS]
                • Tay-Sachs disease (GDGDB) [HEXA]
                • Sandhoff disease (GDGDB) [HEXB]
                • Multiple sulfatase deficiency (GDGDB) [SUMF1]
                • Metachromatic leukodystrophy (GDGDB) [ARSA]
                • Metachromatic leukodystrophy, due to saposin B deficiency (GDGDB) [PSAP]
                • Niemann-Pick disease, type C1 (GDGDB) [NPC1]
                • Niemann-Pick disease, type C2 (GDGDB) [NPC2]
                • Farber Lipogranulomatosis (GDGDB) [ASAH1]
                  • Farber Lipogranulomatosis, type 5 [ASAH1]